Ara h 2 Specific IgA B Cell Repertoire Matures During Peanut Oral Immunotherapy
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چکیده
منابع مشابه
Utility of Specific IgE to Ara h 2 in Italian Allergic and Tolerant Children Sensitized to Peanut
Emerging data suggest that measurement of serum IgE to peanut components can be clinically helpful and more accurate than IgE to whole peanut to predict peanut allergy. Not all studies have used prospective samples, multiple components and oral challenges. Currently, there are no data on this topic involving Italian children. 32 patients (23 males; median age 9 years) with reported history for ...
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The similarities of two major peanut allergens, Ara h 2 and Ara h 6, in molecular size, amino acid sequence, and structure have made it difficult to obtain natural Ara h 6 free of Ara h 2. The objectives of this study were to purify natural Ara h 6 that is essentially free of Ara h 2 and to compare its IgE reactivity and potency in histamine release assays to Ara h 2. Sodium dodecyl sulfate-pol...
متن کاملDiagnostic Value of Specific IgE to Peanut and Ara h 2 in Korean Children with Peanut Allergy
PURPOSE The purpose of this study was to establish the diagnostic decision point (DDP) of peanut specific IgE (sIgE) for predicting the outcome of oral food challenge (OFC). We also evaluated the usefulness of sIgE to peanut components (Ara h 1, 2, 3, 8, and 9) in diagnosing peanut allergy. METHODS Korean children aged over 12 months with a suspected peanut allergy were enrolled. Diagnosis of...
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Peanut allergy is an IgE-mediated adverse reaction to a subset of proteins found in peanuts. Immunotherapy aims to desensitize allergic patients through repeated and escalating exposures for several months to years using extracts or flours. The complex mix of proteins and variability between preparations complicates immunotherapy studies. Moreover, peanut immunotherapy is associated with freque...
متن کاملutility of specific ige to ara h 2 in italian allergic and tolerant children sensitized to peanut
emerging data suggest that measurement of serum ige to peanut components can be clinically helpful and more accurate than ige to whole peanut to predict peanut allergy. not all studies have used prospective samples, multiple components and oral challenges. currently, there are no data on this topic involving italian children. 32 patients (23 males; median age 9 years) with reported history for ...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2020
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2019.12.311